Clinicopathologic Correlation of NACC Diagnosis Lead Investigator: William Hu Institution : Emory University E-Mail : wthu@emory.edu Proposal ID : 473 Proposal Description: There are mixed results regarding the sensitivities and specificities of clinical diagnosis for Alzheimer's disease, dementia with Lewy bodies, behavioral variant frontotemporal dementia, primary progressive aphasia, and Creutzfeldt Jakob disease (CJD). We aim to assess in a large national repository the diagnostic accuracy of clinical syndromic diagnoses including dementia due to Alzheimer's disease, mild cognitive impairment, dementia due to frontotemporal dementia, dementia due to primary progressive aphasia, dementia due to dementia with Lewy bodies, and dementia due to CJD.